Skip to main content
CTOS 2023 Main banner
Final Program


Schedule at a Glance
Icon Legend
This session is not in your schedule.
This session is in your schedule. Click again to remove it.
Back

Session 2: Sarcoma Biology and 'Omics

Thursday, November 2, 2023
11:00 AM – 12:30 PM  

    Chair(s)

  • Maureen O'Sullivan, MBBCh, MD, FRCPath

    Consultant/Professor
    Children's Health Ireland & Trinity College, Dublin, IRELAND
    Dublin, Dublin, Ireland

    • Moderator(s)

  • Alejandro Sweet-Cordero, MD

    Chief of Pediatric Oncology, Department of Pediatrics, UCSF; Professor of Pediatrics;
    UCSF
    San Francisco, California, United States

  • Brian Crompton, MD

    Co-Director for Research, Pediatric Solid Tumor Program Assistant Professor of Pediatrics, Harvard Medical School Associate Member, Broad Institute of Harvard and MIT Dana-Farber/Boston Children’s Cancer and Blood Disorders Center
    Dana-Farber/Boston Children's Cancer and Blood Disorders Center
    Boston, Massachusetts, United States

  • Sarah Watson, MD, PhD

    Clinician Scientist
    Institut Curie
    Paris, Ile-de-France, France

Presentations:

  • 11:00 AM – 12:30 PM  
    AN OSTEOSARCOMA-INDUCED WOUND HEALING RESPONSE IS ESSENTIAL FOR LUNG COLONIZATION DURING METASTASIS AND IS THERAPEUTICALLY TARGETABLE

    Co-Author: James B. Reinecke, MD, PhD – Nationwide Children's Hospital

    Co-Author: Leyre Jimenez Garcia, BS (she/her/hers) – Nationwide Children's Hospital

    Co-Author: Amy C. Gross, MS (she/her/hers) – Nationwide Children's Hospital

    Co-Author: Maren Cam, PhD (she/her/hers) – Nationwide Children's Hospital

    Author: Ryan D. Roberts, MD, PhD – Nationwide Children's Hospital

  • 11:00 AM – 12:30 PM  
    MECHANISMS AND EVOLUTIONARY TRAJECTORIES OF COMPLEX GENOME REARRANGEMENTS IN OSTEOSARCOMA

    Co-Author: Jose Espejo Valle-Inclan, PhD – EMBL-EBI

    Co-Author: Solange de Noon, MD – University College London Cancer Institute

    Co-Author: Katherine Trevers, PhD – Research Department of Pathology, University College London Cancer Institute

    Co-Author: Hillary Elrick, n/a – EMBL-EBI

    Co-Author: Adrienne Margaret Flanagan, MD-PhD (she/her/hers) – University College London, Cancer Institute

    Author: Isidro Cortes-Ciriano, PhD – EMBL-EBI

  • 11:00 AM – 12:30 PM  
    NETWORK-BASED INFERENCE IDENTIFIES PROGNOSTIC SIGNATURES AND DRUGS TARGETING MASTER REGULATORS OF DISTINCT CELL STATES IN OSTEOSARCOMA

    Author: Jovana Pavisic, MD, MA (she/her/hers) – Columbia University Irving Medical Center

    Co-Author: Somnath Tagore, PhD – Columbia University

    Co-Author: Aaron T. Griffin, PhD (he/him/his) – Columbia University

    Co-Author: Inge Behroozfard, n/a – UCSF

    Co-Author: Stanley Leung, BA – UCSF

    Co-Author: Alex Lee, PhD – UCSF

    Co-Author: Leanne Sayles, BS – UCSF

    Co-Author: Katherine A. Janeway, MD – Dana-Farber/Boston Children's Cancer and Blood Disorders Center

    Co-Author: Alejandro Sweet-Cordero, MD – UCSF

    Co-Author: Filemon S. Dela Cruz, MD (he/him/his) – Memorial Sloan Kettering Cancer Center

    Co-Author: Andrew L. Kung, MD, PhD – Memorial Sloan Kettering Cancer Center

    Co-Author: Darrell Yamashiro, MD, PhD – Columbia University Irving Medical Center

    Co-Author: Julia L. Glade Bender, MD (she/her/hers) – Memorial Sloan Kettering Cancer Center

    Co-Author: Andrea Califano, PhD – Department of Systems Biology, Biomedical Informatics, Biochemistry and Molecular Biophysics, and Medicine, Herbert Irving Comprehensive Cancer Center, Columbia University

  • 11:00 AM – 12:30 PM  
    MULTISCALE TRANSCRIPTOMICS REVEALS THE OVERARCHING LANDSCAPE OF MESENCHYMAL NEOPLASMS AND BIOLOGICALLY MEANINGFUL SUBTYPES

    Author: Joshua O. Nash (he/him/his) – The Hospital for Sick Children

    Co-Author: Federico Comitani, PhD – The Hospital for Sick Children

    Co-Author: Astra Schwertschkow, PhD – The Hospital for Sick Children

    Co-Author: Yael Babichev, PhD (she/her/hers) – Sinai Healthcare System

    Co-Author: Jodi Lees, n/a – The Hospital for Sick Children

    Co-Author: Noa Alon, n/a – The Hospital for Sick Children

    Co-Author: Nalan Gokgoz, PhD – The Lunenfeld-Tanenbaum Research Institute

    Co-Author: Olga Vornicova, MD – University Hospital Network

    Co-Author: Zhanqin Liu, n/a – The Hospital for Sick Children

    Co-Author: Miranda Lorenti, n/a – The Hospital for Sick Children

    Co-Author: Alaina McGoey, n/a – The Hospital for Sick Children

    Co-Author: Famida Spatare, n/a – The Hospital for Sick Children

    Co-Author: Bernald Castro, n/a – The Hospital for Sick Children

    Co-Author: Kim Tsoi, MD, PhD – University of Toronto

    Co-Author: Hagit Peretz Soroka, Ph.D. – Princess Margaret Cancer Centre / The Hospital For Sick Children

    Co-Author: Jack Brzezinski, MD – The Hospital for Sick Children

    Co-Author: Anita Villani, MD – The Hospital for Sick Children

    Co-Author: Albiruni Ryan Abdul Razak, MB BCh, BM BCh – Princess Margaret Cancer Center

    Co-Author: Abha Gupta, MD MSc – Princess Margaret Cancer Center

    Co-Author: Elizabeth Demicco, MD, PhD – Sinai Health System

    Co-Author: Jay Wunder, M.Sc, MD – University of Toronto

    Co-Author: Irene Andrulis, PhD – The Lunenfeld-Tanenbaum Research Institute, Sinai Health System University of Toronto

    Co-Author: Marjan Rouzbahman, MD – University Hospital Network

    Co-Author: Jonathon Solnik, MD – Mount Sinai Hospital

    Co-Author: Marcus Bernadini, MD – University Hospital Network

    Co-Author: David Malkin, MD – The Hospital for Sick Children

    Co-Author: Rose Chami, MD – The Hospital for Sick Children; University of Toronto

    Co-Author: Brendan Dickson, BA, BSc, MSc, MD, FCAP – University of Toronto

    Co-Author: Rebecca Gladdy, MD, PhD (she/her/hers) – Mount Sinai Hospital, Sinai Health System, and Princess Margaret Cancer Centre Toronto, ON, Canada Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada University of Toronto, Toronto, ON

    Co-Author: Adam Shlien, PhD, FCCMG – The Hospital for Sick Children

  • 11:00 AM – 12:30 PM  
    INTEGRATING SPATIAL TUMOR PROFILING AND CTDNA ANALYSIS IDENTIFIES EVOLUTIONARY PRESSURES DURING SARCOMA DEVELOPMENT AND RADIOTHERAPY

    Author: Erik Blomain, MD PhD – Thomas Jefferson University

    Co-Author: Shaghayegh Soudi, PhD – Stanford University

    Co-Author: Anish Somani, Undergraduate Student – Stanford University

    Co-Author: Ajay Subramanian, BS – Stanford University

    Co-Author: Neda Nemat-Gorgani, MS – Stanford University

    Co-Author: Everett J. Moding, MD, PhD (he/him/his) – Stanford University

  • 11:00 AM – 12:30 PM  
    MIR-449A/340 REWIRE METABOLIC COMMITMENT OF FUSION-NEGATIVE RHABDOMYOSARCOMA VIA MITOCHONDRIAL PYRUVATE CARRIER INHIBITION

    Author: Enrico Pozzo, MD, PhD – Translational Cardiomyology Laboratory, Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven; Leuven Cancer Institute (LKI)

    Co-Author: Laura Yedigaryan, Master, PhD student (she/her/hers) – Translational Cardiomyology Laboratory, Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven

    Co-Author: Nefele Giarratana, PhD – Translational Cardiomyology Laboratory, Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven

    Co-Author: Chao-Chi Wang, PhD student (she/her/hers) – Laboratory of Experimental Oncology, KU Leuven, Leuven Cancer Institute

    Co-Author: Gabriel Miró Garrido, n/a – Translational Cardiomyology Laboratory, Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven

    Co-Author: Ewoud Degreef, n/a – Translational Cardiomyology Laboratory, Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven

    Co-Author: Vittoria Marini, Master, PhD student – Translational Cardiomyology Laboratory, Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven

    Co-Author: Gianmarco Rinaldi, PhD – Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI)

    Co-Author: Bernard Van der Veer, Master, PhD student – Laboratory of Stem Cell and Developmental Epigenetics, Department of Development and Regeneration, KU Leuven

    Co-Author: Gabriele Sassi, Master, PhD student – Clinical and Experimental Endocrinology (CEE), KU Leuven

    Co-Author: Guy Eelen, PhD – Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven

    Co-Author: Mélanie Planque, n/a – Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI)

    Co-Author: Alessandro Fanzani, PhD – Department of Molecular and Translational Medicine, University of Brescia

    Co-Author: Kian Peng Koh, PhD – Laboratory of Stem Cell and Developmental Epigenetics, Department of Development and Regeneration, KU Leuven

    Co-Author: Peter Carmeliet, MD, PhD – Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven

    Co-Author: Jason Yustein, MD, PhD – Aflac Cancer and Blood Disorders Center, Emory University

    Co-Author: Sarah-Maria Fendt, PhD – Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI)

    Co-Author: Anne Uyttebroeck, MD, PhD – Department of Pediatric Hemato-Oncology, UZ Leuven

    Co-Author: Maurilio Sampaolesi, PhD – Translational Cardiomyology Laboratory, Stem Cell and Developmental Biology Unit, Department of Development and Regeneration, KU Leuven

  • 11:00 AM – 12:30 PM  
    DNA BINDING DOMAIN OF EWS::FLI REGULATES TRANSCRIPTION VIA MODULATION OF CHROMATIN 3D LANDSCAPE IN EWING SARCOMA

    Author: Ariunaa Bayanjargal, B.S – Nationwide Childrens Hospital

    Co-Author: Cenny Taslim, PhD – nationwide childrens hospital

    Co-Author: Jesse Crow, B.S. – Forge Biologics

    Co-Author: Julia Selich-Anderson, M.S – Forge Biologics

    Co-Author: Emily R. Theisen, PhD – Nationwide Childrens Hospital

    Co-Author: Stephen Lessnick, MD, PhD – Nationwide Children's Hospital

  • 11:00 AM – 12:30 PM  
    A SINGLE-CELL TRANSCRIPTOMICS COMPUTATIONAL PIPELINE UNVEILS THE LANDSCAPE OF CAR-T CELL TARGETS IN SOFT TISSUE SARCOMA

    Author: Stefano Testa, MD (he/him/his) – Beth Israel Deaconess Medical Center

    Co-Author: Minggui Pan, MD (he/him/his) – Stanford University

    Co-Author: Nam Bui, MD – Stanford University

    Co-Author: Kristen N. Ganjoo, MD – Stanford Cancer Center

    Co-Author: Matt van de Rijn, M.D. (he/him/his) – Stanford University

    Co-Author: Anusha Kalbasi, M.D. – Stanford University

    Co-Author: Everett J. Moding, MD, PhD (he/him/his) – Stanford University