Session 14: GIST

Chair(s)

• 

  Herbert Ho Fung Loong, MBBS(HK), PDipMDPath(HK), MRCP(UK), FRCP Edin, FHKCP, FHKAM(Medicine) (he/him/his)

  Clinical Associate Professor
  The Chinese University of Hong Kong
  Hong Kong, Hong Kong

Moderator(s)

• 

  Chandrajit Raut, MD, MSc, FACS, FSSO (he/him/his)

  Surgical Oncologist
  Brigham and Women’s Hospital/Harvard Medical School
  Boston, Massachusetts, United States
• 

  Anette Duensing, MD

  Associate Professor
  University of Pittsburgh School of Medicine
  Pittsburgh, Pennsylvania, United States
• 

  Toto Hølmebakk, MD, PhD (he/him/his)

  Consultant Surgeon
  Oslo University Hospital, The Norwegian Radium Hospital
  Oslo, Oslo, Norway

Presentations:

• 3:00 PM – 4:00 PM  

  AN OPEN-LABEL, PHASE II EFFICACY STUDY OF TEMOZOLOMIDE IN ADVANCED SUCCINATE DEHYDROGENASE-MUTANT/DEFICIENT GASTROINTESTINAL STROMAL TUMOR
  

  Author: Adam M. Burgoyne, MD, PhD – UC San Diego Moores Cancer Center

  Co-Author: Michael C. Heinrich, MD – Portland VA Health Care System and Oregon Health & Science University Knight Cancer Institute

  Co-Author: Margaret von Mehren, MD (she/her/hers) – Fox Chase Cancer Center

  Co-Author: Jonathan Trent, MD, PhD – Sylvester Comprehensive Cancer Center, University of Miami

  Co-Author: Paul T. Fanta, MD – Department of Medicine, Division of Medical Oncology, University of California San Diego

  Co-Author: Michael Hahn, MD, PhD – UC San Diego Moores Cancer Center

  Co-Author: Christian Metallo, PhD – Salk Institute for Biological Studies

  Co-Author: Elaine Eng, FNP-BC, MSN – UC San Diego Moores Cancer Center

  Co-Author: Minya Pu, PhD – UC San Diego Moores Cancer Center

  Co-Author: Emily Pittman, PhD – UC San Diego Moores Cancer Center

  Co-Author: Karen Messer, PhD – UC San Diego Moores Cancer Center

  Co-Author: Jason K. Sicklick, M.D., FACS – Department of Surgery, Division of Surgical Oncology, University of California San Diego
• 3:00 PM – 4:00 PM  

  A PHASE 2 STUDY OF ROGARATINIB (BAY 1163877) IN SOFT TISSUE SARCOMAS: INITIAL RESULTS IN COHORT OF PATIENTS WITH SUCCINATE DEHYDROGENASE (SDH)-DEFICIENT GASTROINTESTINAL STROMAL TUMOR (GIST)
  

  Author: Priscilla Merriam, MD – Dana-Farber Cancer Institute

  Co-Author: Emanuele Mazzola, PhD – Dana-Farber Cancer Institute

  Co-Author: Ping Chi, MD, PhD (she/her/hers) – Memorial Sloan Kettering Cancer Center

  Co-Author: Alice Chen, MD – Division of Cancer Treatment and Diagnosis, National Cancer Institute

  Co-Author: Mark Agulnik, MD (he/him/his) – City of Hope, Department of Medical Oncology & Therapeutics Research

  Co-Author: Melissa A. Burgess, MD (she/her/hers) – University of Pittsburgh Medical Center Hillman Cancer Center

  Co-Author: Scott M. Schuetze, MD, PhD – University of Michigan

  Co-Author: Neeta Somaiah, MD (she/her/hers) – The University of Texas MD Anderson Cancer Center

  Co-Author: Brian Andrew Van Tine, MD, PhD (he/him/his) – Washington University School of Medicine

  Co-Author: Seth Pollack, MD – Robert H. Lurie Comprehensive Cancer Center of Northwestern University

  Co-Author: Gabriel Tinoco, MD – The Ohio State University Comprehensive Cancer Center

  Co-Author: Jonathan Trent, MD, PhD – Sylvester Comprehensive Cancer Center, University of Miami

  Co-Author: Breelyn A. Wilky, MD (she/her/hers) – University of Colorado Cancer Center

  Co-Author: Nicola Bothwick, BA – Dana-Farber Cancer Institute

  Co-Author: Richard Piekarz, MD, PhD – Division of Cancer Treatment and Diagnosis, National Cancer Institute

  Co-Author: Matthew L. Hemming, MD, PhD – UMass Chan Medical School

  Co-Author: Bradley Bernstein, MD, PhD – Dana-Farber Cancer Institute, Ludwig Center at Harvard Medical School

  Co-Author: Geoffrey I. Shapiro, MD, PhD – Dana-Farber Cancer Institute, Ludwig Center at Harvard Medical School

  Co-Author: George Demetri, MD (he/him/his) – Dana-Farber Cancer Institute, Ludwig Center at Harvard Medical School

  Co-Author: Suzanne George, MD – Dana-Farber Cancer Institute
• 3:00 PM – 4:00 PM  

  RECURRENCE-FREE SURVIVAL IN GASTROINTESTINAL STROMAL TUMORS IS CORRELATED WITH MUTATION TYPE: RESULTS FROM THE LIFE RAFT GROUP PATIENT REGISTRY
  

  Co-Author: Denisse A. Evans, MSc – The Life Raft Group

  Author: Jerry W. Call (he/him/his) – The Life Raft Group

  Co-Author: Sahibjeet Parmar, MPH – The Life Raft Group

  Co-Author: Sara Rothschild, M.P.H. – The Life Raft Group
• 3:00 PM – 4:00 PM  

  APPLICATION OF SINGLE NUCLEI RNA-SEQUENCING OF HUMAN GASTROINTESTINAL STROMAL TUMORS TO DEFINE TUMOR CELL STATES FOR INFERRING INTRA- AND INTER-TUMORAL HETEROGENEITY FROM BULK TRANSCRIPTOMES
  

  Author: Ashwyn K. Sharma, M.D. – Department of Surgery, Division of Surgical Oncology, University of California San Diego

  Co-Author: Alexander T. Wenzel, B.S. – Department of Medicine, University of California San Diego

  Co-Author: John Jun, B.S. – Department of Medicine, University of California San Diego

  Co-Author: Diwakar Guragain, PhD (he/him/his) – Department of Surgery, Division of Surgical Oncology, University of California San Diego

  Co-Author: Chih-Min Tang, Ph.D. – Department of Surgery, Division of Surgical Oncology, University of California San Diego

  Co-Author: Shruti Bhargava, Ph.D. – Department of Surgery, Division of Surgical Oncology, University of California San Diego

  Co-Author: Adam M. Burgoyne, MD, PhD (he/him/his) – Department of Medicine, Division of Hematology-Oncology, UC San Diego Health

  Co-Author: Paul T. Fanta, MD – Department of Medicine, Division of Medical Oncology, University of California San Diego

  Co-Author: Sadie E. Munter, B.A. – Department of Surgery, University of California San Diego

  Co-Author: Katherine Y. Chen, B.S. – Department of Surgery, University of California San Diego

  Co-Author: Terrence M. Doherty, B.A. – Moores Cancer Center, University of California San Diego

  Co-Author: Manikandan Murugesan, PhD (he/him/his) – Department of Surgery, Division of Surgical Oncology, University of California San Diego

  Co-Author: Adrian Sanchez-Fdez, PhD – Department of Surgery, Division of Surgical Oncology, University of California San Diego

  Co-Author: Shashwath Kalladi Malli, PhD – Department of Surgery, Division of Surgical Oncology, University of California San Diego

  Co-Author: Prabhjot S. Mundi, M.D. – Department of Medicine, Columbia University

  Co-Author: Sara Rothschild, M.P.H. – The Life Raft Group

  Co-Author: Denisse Evans, M.S. – The Life Raft Group

  Co-Author: William Kim, Ph.D. – Department of Medicine, University of California San Diego

  Co-Author: Gary K. Schwartz, MD – Herbert Irving Comprehensive Cancer Center at Columbia University School of Medicine

  Co-Author: Andrea Califano, PhD – Department of Systems Biology, Biomedical Informatics, Biochemistry and Molecular Biophysics, and Medicine, Herbert Irving Comprehensive Cancer Center, Columbia University

  Co-Author: Pablo Tamayo, Ph.D. – Department of Medicine, University of California San Diego

  Co-Author: Jill P. Mesirov, PhD – Department of Medicine, Division of Genomics and Precision Medicine, University of California San Diego

  Co-Author: Jason K. Sicklick, M.D., FACS – Department of Surgery, Division of Surgical Oncology, University of California San Diego
• 3:00 PM – 4:00 PM  

  SEVERE FEAR OF RECURRENCE OR PROGRESSION, SYMPTOMS OF ANXIETY AND DEPRESSION IN GASTROINTESTINAL STROMAL TUMOR (GIST) PATIENTS IN THE NETHERLANDS: DATA FROM A CROSS-SECTIONAL MULTICENTER STUDY
  

  Author: Deborah van de Wal, MD – Netherlands Cancer Institute/ Antoni van Leeuwenhoek

  Co-Author: Dide den Hollander, MD, PhD (she/her/hers) – Radboud University Medical Center

  Co-Author: Ingrid M. Desar, MD PhD – Radboud University Medical Center

  Co-Author: Hans Gelderblom, MD, PhD (he/him/his) – Leiden University Medical Center

  Co-Author: Astrid W. Oosten, MD PhD (she/her/hers) – Erasmus MC Cancer Institute

  Co-Author: An Reyners, Prof. Dr. – University medical center Groningen

  Co-Author: Neeltje Steeghs, Dr. – Netherlands Cancer Institute/ Antoni van Leeuwenhoek

  Co-Author: Winette T. van der Graaf, Prof. Dr. – Netherlands Cancer Institute/ Antoni van Leeuwenhoek

  Co-Author: Olga Husson, PhD (she/her/hers) – Netherlands Cancer Institute