(P 561) EXPERIENCE OF PHYSICAL DISABILITIES AND CANCER-RELATED QUALITY OF LIFE AFTER SPINAL TUMORS- STUDY OF A NATIONAL SURVEY IN ENGLAND.

Objective: 1) To investigate extent of disability and activity limitations experienced by patients with spinal tumors using the Sarcoma Assessment Measure (SAM) questionnaire, European Organization for the Research and Treatment of Cancer QoL Questionnaire (EORTC QLQ C30), and Toronto Extremity Salvage Score (TESS).
2) To investigate how the QoL varies with age, gender, tumor type and location, treatment type, time since diagnosis, and employment status.

Methods: A cross-sectional study design was performed to collect data from 25 patients diagnosed with spinal tumors. The participants completed the SAM questionnaire, EORTC QLQ C30, Global Rating Change Scale and TESS, which provided comprehensive assessments of disability levels, activity limitations, and QoL. The demographic and clinical information, including age, tumor type and location, treatment type, time since diagnosis, and employment status, were also collected similarly.
Domain scores for each of the questionnaires were calculated and statistical analyses including chi-square, Mann Whitney U, and Kruskal Wallis tests, will be utilized to determine whether any significant differences exist between disability levels and activity limitations across different demographic and clinical factors.

Results: The results show a wide variation in disability levels and activity limitations. A higher score for the SAM questionnaire indicates less deterioration. High scores for the functional and global scales indicate a better functioning and QoL, whereas high scores for the symptom scales indicate more intense symptoms. A higher score for TESS indicates increased difficulty in performing the tasks. Statistical analyses will be done to determine whether disability levels and activity limitations vary significantly based on age, gender, tumor type and location, treatment type, time since diagnosis, and employment status.

Conclusion: This study is being carried out to determine the degree to which spinal tumors impact disability levels and activity limitations in patients, encompassing physical, psychological, and social aspects. The multidimensional approach, involving the SAM questionnaire, EORTC QLQ C30, and TESS, will provide a comprehensive understanding of the patients' experiences. The findings will highlight the importance of considering demographic and clinical factors when evaluating disability and activity limitations. The unique challenges faced by individuals in this group, including the need for assistive devices, physical therapy, and emotional support, necessitate an integrated approach to rehabilitation. Understanding the unique features, correlations, and everyday difficulties faced by individuals with spinal sarcoma is essential for developing targeted interventions, improving treatment outcomes, and enhancing overall QoL. Building a strong support network and accessing comprehensive rehabilitation services are crucial for spinal sarcoma patients.