Associate Staff
Cleveland Clinic
Cleveland, Ohio, United States
Josephine Dermawan, MD, PhD is an attending pathologist and medical director for Anatomic Pathology Molecular Services at Cleveland Clinic. She completed subspecialty training in Bone and Soft Tissue Pathology at Cleveland Clinic and Molecular Genetic Pathology at Memorial Sloan Kettering Cancer Center. Dr. Dermawan is particularly interested in the histologic and molecular characterization and discovery of novel and rare soft tissue entities, and the use of next-generation sequencing techniques to complement and augment traditional clinicopathologic investigative methods. Her research focuses on deciphering the genomics and epigenomics of emerging and established soft tissue and bone tumors, and their translational applications, including novel risk stratification and therapeutic target discoveries, in the diagnosis, prognostication, and management of these rare but fascinating entities. Recently, she led a project on the development of a novel genomic risk stratification model using genomic profiling and machine learning-based computational tools for gastrointestinal stromal tumors (GIST) in the imatinib era. She is currently working on investigating chromoplexy as a frequent and early genomic event in EWSR1-rearranged small round blue cell tumors. She is also investigating the use of single cell and spatial transcriptomics to decipher developmental lineages and cell states in different leiomyosarcoma subtypes and spindle cell rhabdomyosarcoma. In 2023, Dr. Dermawan received a Leiomyosarcoma SPORE Career Enhancement Program award.
Disclosure information not submitted.
Saturday, November 4, 2023
4:30 PM – 6:00 PM
Saturday, November 4, 2023
4:30 PM – 6:00 PM