Staff Scientist
Fondazione IRCCS Istituto Nazionale dei Tumori, Italy
Dr DeCecco, is a molecular biologist with twenty-five years of translational research experience using cutting-edge genomics technologies.
In 2000, he moved to IFOM (Milan, Italy) and he was involved in the experimental design, execution, and bioinformatics analysis in numerous gene-expression and miRNA studies using the Illumina and Agilent microarray platforms. Starting from early 2010s, he was involved in next generation sequencing projects through short-read and/or long-read sequencing technologies using different biological materials (i.e. tissue fresch frozen or FFPE, liquid biopsies, stool) and covering the most relevant applications: i) transcriptomics (i.e. coding and long.non coding RNA, splice variants, transcript fusions) with different RNAseq approaches both bulk and single-cell levels (Parse Bioscences); ii) CNV/mutations/genotyping with target resequencing, WES, and WGS; iii) epigenomics (i.e. methylation, miRNA, chromatin functional assays) with WGBS-Seq, RRBS-Seq, nanopore, smallRNAseq, ATAC-Seq; iv) metagenomics (i.e. 16S, shotgun) and metatranscriptomics; v) spatial-omics (Visium, 10X Genomics).
He has been involved in both experimental and bioniformatics analyses in different types of tumors including ovarian cancer, sarcoma, thyroid cancer and breast cancer in collaboration with institutional and other national research groups. He awarded his PhD in 2009 (supervisor: Dr. M.A. Pierotti). From then on, he focused his interest on translational research n head and neck cancer and brain pediatric tumors.
His commitment and scientific independence is proven by the publication of about 160 peer reviewed paper (Hindex: 36 by Scopus; ORCID ID: 0000-0002-7066-473X).
