Post-doctoral fellow
University of Kansas Medical Centre
My research interests involve studying the molecular and cellular alterations in cancer and targeting the oncogenic pathways by identifying novel druggable targets that are effective in suppressing tumor progression. My academic training and research experience have provided me with an excellent background in diverse biological areas including cell and molecular biology, biochemistry, genetics, stem cell biology, cancer stem cells, tumor biology with a focus in adult (glioblastoma) and pediatric tumors (Ewing sarcoma). After completing my undergraduate studies, I had the opportunity to work in reputed laboratories such as Indian Institute of Chemical Technology where I learned basics in gene cloning while working on the gene Nrf2. My work as an intern at Institute of Genetics and Hospital for genetic diseases helped me understand the role of mutations in disease progression and screening for mutant alleles in pregnant female patients diagnosed with Preeclampsia. I had the opportunity to study the role of mesenchymal stem cells in tissue regeneration during my role as a Research Assistant in Center for Cellular and Molecular Biology (CCMB). My graduate work focused on identifying novel interaction in cancer stem cells (CSCs) and role of sex-specific differences in glioblastoma progression. In my post-doctoral studies, I developed techniques and concepts related to isolation and characterization of proteomes of small extracellular vesicles derived from Ewing sarcoma (EWS) cells. I also worked on identifying drug combinations that have synergistic effect in inhibiting EWS tumor growth.
