Research Scientist
The Jackson Laboratory for Genomic Medicine
In his current role as a Research Scientist at The Jackson Laboratory for Genomic Medicine, Dr. Ng leads pioneering research projects aimed at advancing our understanding of complex diseases, particularly osteosarcoma. His work involves cutting-edge techniques such as single-cell RNA sequencing and spatial transcriptomic analysis to unravel the intricacies of tumor microenvironments and heterogeneity. Additionally, he investigates alternative splicing events using Long-read RNA sequencing, with the ultimate goal of identifying novel biomarkers for treatment response, metastasis, and survival in osteosarcoma patients. His contributions extend to the exploration of new therapeutic targets, including immunotherapy. In addition, Dr. Ng has actively participated in several critical projects, notably the discovery of biomarkers in cerebrospinal fluid for Intracranial germ cell tumor patients and the study of treatment-related ototoxicity inheritability.
In the past positio, Dr. Ng has led the development of a platform for testing the functional effects of mutations, many of which were identified through large-scale tumor sequencing projects like The Cancer Genome Atlas (TCGA). Dr. Ng's collaborative efforts resulted in the construction of over 1,600 mutation clones and the publication of invaluable data in Cancer Cell journal, providing a valuable resource for the broader research community.
