Benjamin S. Fletcher, BA

Research Technician
The West German Cancer Centre, University Hospital Essen, Germany

I have worked for two years as a research technician in the lab of Dr. Sebastian Bauer, West German Cancer Centre, University Hospital Essen, Germany. During this time my work focused on using CRISPR/Cas9 to model the heterogeneity of primary and secondary resistance mutations in GIST, and carrying out large-scale compound screens in cell line models. I am currently continuing my studies at the University of Edinburgh, but remain an active collaborator with the Bauer lab in Essen.

Poster(s):

• (P 275) GIST-BSF1: A NOVEL SCF-DEPENDENT, WILD-TYPE KIT CELL LINE PLATFORM THAT ALLOWS RAPID GENERATION OF ISOGENIC SUBLINES WITH BOTH IMATINIB-SENSITIVE AND IMATINIB-RESISTANT GENOTYPES

• (P 276) REVISITING IN- AND OFF LABEL DRUGS FREQUENTLY USED IN METASTATIC GIST USING A BROAD IN VITRO PROFILING PANEL OF PRIMARY AND SECONDARY KIT AND PDGFRA-MUTANT GIST CELLS – CLINICAL IMPLICATIONS