Associate Professor
Dana-Farber and Children's Hospital
Boston, Massachusetts, United States
Dr. Janeway received her MD from Harvard Medical School in 2000 and a Masters of Medical Science also from Harvard in 2008. She completed her pediatrics residency at Boston Children’s Hospital, where she was Chief Resident. Dr. Janeway then completed her fellowship in Pediatric Hematology-Oncology and was Chief Fellow at Dana-Farber Cancer Institute in Boston. Dr. Janeway is an Associate Professor of Pediatrics at Harvard Medical School, a Senior Physician in pediatric oncology at Dana-Farber/Boston Children’s and Director of Clinical Genomics at Dana-Farber Cancer Institute.
Dr. Janeway’s research is focused on genomics, precision oncology and bone sarcomas. She leads clinical trials in osteosarcoma and Ewing sarcoma both as an independent investigator and as the Chair of the Children’s Oncology Group (COG) Bone Tumor Committee. She has led the development of more than 10 clinical trials and been an investigator in an additional 5 trials in osteosarcoma and Ewing sarcoma. With the COG, she developed a now widely accepted benchmark facilitating the efficient conduct of phase 2 clinical trials in recurrent osteosarcoma. She is also part of the leadership team of the first and largest national precision oncology trial in the United States, the National Cancer Institute-COG Pediatric MATCH trial.
The Janeway Laboratory focuses on genomics, precision oncology, and bone sarcomas. Their work has uncovered the genomic events causing and sustaining difficult-to-treat childhood solid malignancies. The laboratory leads the 12-institution iCat2/GAIN consortium study, which has enrolled and sequenced more than 800 patients with rare, difficult-to-treat childhood solid cancers 75% of which have sarcomas. They aim to use this data to deepen the understanding of clinical and genomic factors explaining prognosis and treatment response and resistance in bone sarcomas. In collaboration with the Broad Institute and Count Me In, the group is innovating patient partnerships in sarcoma research.
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Herman Suit Lecture: Why I Sequence the Cancer Genome of all Pediatric and AYA Sarcomas
Friday, November 3, 2023
2:00 PM - 2:30 PM
